Recent interest by scholars in the ocean and its complex geographies has not been directed much towards the everyday life of those on board fishing vessels and how they sense the nature around them. A large trawler for oceanic fishing is a highly efficient industrial production machine, carrying an array of equipment that mediates the connection between crew and nature. This article presents results from an experimental research project, where one of the authors joined a fishing trip on an Icelandic (...) factory trawler. The resulting rich set of ethnographic material reveals much about the particularities of being at sea. It is argued that the ship can be understood as a series of distinct taskscapes, each of which affords certain relations between human and non-human nature. (shrink)

The first of these two volumes is a second edition of the first part of Jonas' comprehensive scholarly study of Gnosticism, first published in 1934. Except for minor corrections the first edition has been left unrevised. The second volume carries the study up to the third century A.D. A final volume completing the second part is promised for the near future.--R. H.

In this work R. M. Martin carries his semiotical studies into the fields of intensional semantics and pragmatics, dealing with such philosophically important concepts as meaning, preference, reasonableness and indifference. The crucial notion is that of the meaning or intension of an expression. Two major categories are distinguished, objective intensions and subjective intensions. To deal with objective intensions an intensional semantics is developed as an extension of denotational semantics in the tradition of Tarski, Carnap and Martin's earlier Truth and Denotation. (...) In the treatment of subjective intensions Martin makes an advance over his earlier study of pragmatics by utilizing the work of von Neumann and Morgenstern in their Theory of Games and Economic Behavior.—R. H. K. (shrink)

In this work R. M. Martin carries his semiotical studies into the fields of intensional semantics and pragmatics, dealing with such philosophically important concepts as meaning, preference, reasonableness and indifference. The crucial notion is that of the meaning or intension of an expression. Two major categories are distinguished, objective intensions and subjective intensions. To deal with objective intensions an intensional semantics is developed as an extension of denotational semantics in the tradition of Tarski, Carnap and Martin's earlier Truth and Denotation. (...) In the treatment of subjective intensions Martin makes an advance over his earlier study of pragmatics by utilizing the work of von Neumann and Morgenstern in their Theory of Games and Economic Behavior.—R. H. K. (shrink)

This book considers some of the problems of a logical nature about reference which have troubled contemporary philosophers--particularly problems about existence, identity, and definite descriptions. It deals with five philosophers who have been especially concerned with these logical problems: Meinong, Frege, Russell, Strawson, and Quine. The pivotal chapters concern Russell's theory of descriptions and Strawson's well-known critique of that theory in his paper "On Referring." According to Linsky, some of Strawson's criticisms of Russell hit their mark; but not all of (...) them do, because Russell and Strawson turn out to have "compatible views about different subjects". Strawson is concerned with certain uses of words, Russell with propositions of certain kinds. Linsky's arguments on these matters are challenging precisely because they turn some of Strawson's own assumptions against him. But Strawsonians would surely want to carry the argument beyond this book by demanding a more thorough defense of the usefulness of introducing propositions into philosophical analysis as Russell does. Other noteworthy discussions of the book concern the consequences of Frege's semantics, substitutivity and impure reference in the chapter on Quine, and a discussion of extensionality and descriptions.--R. H. K. (shrink)

The author is a Czech physiologist who has given many years of experimental study to the temporal sense in man. He reviews the psychological literature on the sense of time, then describes his own experiments and the theory which he thinks explains them. He believes there are biological rhythms which determine our physiological sense of time and in particular that the alpha rhythm of the brain provides the fundamental reference rhythm by which the organism measures time. This rhythm is autonomous, (...) unchanging in the course of time, present when not evident externally and thus very suitable for time measurement. Experimental evidence for this view reported in the book concerns laborious studies of temporally conditioned reflexes in man carried out by the author over a number of years. He hedges his conclusions and concedes that there is much more work to be done, but his work is both interesting and important. There is little philosophizing in the book, but there is much of philosophical importance.--R. H. K. (shrink)

A critical review of gravitational wave theory is made. It is pointed out that the usual linear approach to the gravitational wave theory is neither conceptually consistent nor mathematically justified. Relying upon that analysis it is argued that—analogously to a Yang-Mills propagating field, which must be nonlinear to carry its gauge charge—a gravitational wave must necessarily be nonlinear to transport its own charge—that is, energy-momentum.

The present paper aims to validate our research on human–humanoid interaction (HHI) using the minimalist humanoid robot Telenoid. We conducted the human–robot interaction test with 142 young people who had no prior interaction experience with this robot. The main goal is the analysis of the two social dimensions (‘‘Perception’’ and ‘‘Believability’’) useful for increasing the natural behaviour between users and Telenoid.Weadministered our custom questionnaire to human subjects in association with a well defined experimental setting (‘‘ordinary and goal-guided task’’). A thorough (...) analysis of the questionnaires has been carried out and reliability and internal consistency in correlation between the multiple items has been calculated. Our experimental results show that the perceptual behaviour and believability, as implicit social competences, could improve the meaningfulness and the natural-like sense of human–humanoid interaction in everyday life task-driven activities. Telenoid is perceived as an autonomous cooperative agent for a shared environment by human beings. (shrink)

Background: The Declaration of Helsinki, the World Medical Association’s statement of ethical guidelines regarding medical research, is published in the three official languages of the WMA: English, French and Spanish.Methods: A detailed comparison of the three official language versions was carried out to determine ways in which they differed and ways in which the wording of the three versions might illuminate the interpretation of the document.Results: There were many minor linguistic differences between the three versions. However, in paragraphs 1, 6, (...) 29, 30 and in the note of clarification to paragraph 29, there were differences that could be considered potentially significant in their ethical relevance.Interpretation: Given the global status of the Declaration of Helsinki and the fact that it is translated from its official versions into many other languages for application to the ethical conduct of research, the differences identified are of concern. It would be best if such differences could be eliminated but, at the very least, a commentary to explain any differences that are unavoidable on the basis of language or culture should accompany the Declaration of Helsinki. This evidence further strengthens the case for international surveillance of medical research ethics as has been proposed by the WMA. (shrink)

An important factor in judging whether two retinal images arise from the same object viewed from different positions may be the presence of certain properties or cues that are 'qualitative invariants' with respect to the natural transformations, particularly affine transformations, associated with changes in viewpoint. To test whether observers use certain affine qualitative cues such as concavity, convexity, collinearity, and parallelism of the image elements, a 'same-different' discrimination experiment was carried out with planar patterns that were defined by four points (...) either connected by straight line segments (line patterns) or marked by dots (dot patterns). The first three points of each pattern were generated randomly; the fourth point fell on their diagonal bisector. According to the position of that point, the patterns were concave, triangular (three points being collinear), convex, or parallel sided. In a 'same' trial, an affine transformation was applied to one of two identical patterns; in a 'different' trial, the affine transformation was applied after the point lying on the diagonal bisector was perturbed a short, fixed distance along the bisector, inwards for one pattern and outwards for the other. Observers' ability to discriminate 'same' from 'different' pairs of patterns depended strongly on the position of the fourth, displaced, point: performance varied rapidly when the position of the displaced point was such that the patterns were nearly triangular or nearly parallel sided, consistent with observers using the hypothesised qualitative cues. The experimental data were fitted with a simple probabilistic model of discrimination performance that used a combination of these qualitative cues and a single quantitative cue. (shrink)

Language does not have to be held as a problem for radical enactivists. The scope objection usually presented to criticize enactivist explanations is a problem only if we have a referentialist and representationalist view of the nature of language. Here we present a normative hypothesis for the great question concerning the hard problem of content, namely, on how linguistic practices develop from minds without content. We carry representational content when we master inferential relations and we master inferential relations when we (...) master normative relations, especially when we are introduced into frameworks of authorizations and prohibitions. Inspired by the anti-intellectualism of the later Wittgenstein and Brandom’s inferentialism, we present the hypothesis that language emerges from inferentially articulated action from normative elements and not from manipulation in internal mental states of contents fixed by reference to external things. (shrink)

In this study, some new hypotheses and techniques are presented to obtain some new analytical solutions to the generalized Kawahara equation. As a particular case, some traveling wave solutions to both Kawahara equation and modified Kawahara equation are derived in detail. Periodic and soliton solutions to this family are obtained. The periodic solutions are expressed in terms of Weierstrass elliptic functions and Jacobian elliptic functions. For KE, some direct and indirect approaches are carried out to derive the periodic and localized (...) solutions. For mKE, two different hypotheses in the form of WSEFs are used to derive the periodic and localized solutions. Also, the cnoidal wave solutions in the form of JEFs are obtained. As a realistic physical application, the solutions obtained can be dedicated to studying many nonlinear waves that propagate in plasma. (shrink)

Phidias’ absence from the survey of sculptors in Cic. Brut. 70 is curious, explanation in terms of differing histories of sculpture only partly convincing. I suggest that Cicero has valid literary motives and is wittily undermining the Atticist position by adaptation of what was a rhetorical topos, the parallel development of Greek prose and sculpture from archaic spareness to classical expertise and dignity: see Dem. Eloc. 14, D. H. Isoc. 3, p.59 U-R; more elaborate but partly deriving from Cicero and (...) less homogeneous is Qu. 12.10.7–9. Cicero assumes the reader's knowledge of the commonplace, pointedly ignores the quality of grandeur and dignity, and develops a theory of technical progress on the basis of veritas and grace to attack the Atticists from their own preferences. The resulting model serves to demote Lysias, imitated by the Atticists but merely the counterpart of Calamis, strigosior like archaic sculptures and superseded by later progress. The analogy thus obliquely repeats the brief but charged parenthesis in 66 that Demosthenes superseded Lysias. (shrink)

Phidias’ absence from the survey of sculptors in Cic. Brut. 70 is curious, explanation in terms of differing histories of sculpture only partly convincing. I suggest that Cicero has valid literary motives and is wittily undermining the Atticist position by adaptation of what was a rhetorical topos, the parallel development of Greek prose and sculpture from archaic spareness to classical expertise and dignity: see Dem. Eloc. 14, D. H. Isoc. 3, p.59 U-R; more elaborate but partly deriving from Cicero and (...) less homogeneous is Qu. 12.10.7–9. Cicero assumes the reader's knowledge of the commonplace, pointedly ignores the quality of grandeur and dignity, and develops a theory of technical progress on the basis of veritas and grace to attack the Atticists from their own preferences. The resulting model serves to demote Lysias, imitated by the Atticists but merely the counterpart of Calamis, strigosior like archaic sculptures and superseded by later progress. The analogy thus obliquely repeats the brief but charged parenthesis in 66 that Demosthenes superseded Lysias. (shrink)

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

In this article, an ethical analysis of an educational programme on renal replacement therapy options for patients and their social network is presented. The two main spearheads of this approach are: (1) offering an educational programme on all renal replacement therapy options ahead of treatment requirement and (2) a home-based approach involving the family and friends of the patient. Arguments are offered for the ethical justification of this approach by considering the viewpoint of the various stakeholders involved. Finally, reflecting on (...) these ethical considerations, essential conditions for carrying out such a programme are outlined. The goal is to develop an ethically justified and responsible educational programme. (shrink)

The 1940s and 1950s were marked by intense debates over the origin of drug resistance in microbes. Bacteriologists had traditionally invoked the notions of ‘training’ and ‘adaptation’ to account for the ability of microbes to acquire new traits. As the field of bacterial genetics emerged, however, its participants rejected ‘Lamarckian’ views of microbial heredity, and offered statistical evidence that drug resistance resulted from the selection of random resistant mutants. Antibiotic resistance became a key issue among those disputing physiological vs. genetic (...) explanations of variation in bacteria. Postwar developments connected with the Lysenko affair gave this debate a new political valence.Proponents of the neo-Darwinian synthesis weighed in with support for the genetic theory. However, certain features of drug resistance seemed inexplicable by mutation and selection, particularly the phenomenon of ‘multiple resistance’—the emergence of resistance in a single strain against several unrelated antibiotics. In the late 1950s, Tsutomu Watanabe and his collaborators solved this puzzle by determining that resistance could be conferred by cytoplasmic resistance factors rather than chromosomal mutation. These R factors could carry resistance to many antibiotics and seemed able to promote their own dissemination in bacterial populations. In the end, the vindication of the genetic view of drug resistance was accompanied by a recasting of the ‘gene’ to include extrachromosomal hereditary units carried on viruses and plasmids. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:J. H. Hexter 1910–1996Donald R. KelleyJ. H. Hexter, one of the leading intellectual historians of this century and a close associate of this Journal, died on 8 December 1996. Jack Hexter was a great scholar, talented writer and polemicist, devoted baseball fan, and authentic American humorist, who made wit and facetiousness part of his historiographical tool-kit. He was also an American character, as he made insistently clear in his (...) writings, especially his autobiographical account, “By Any Other Name,” which explained (among other things) why he came to be called “Jack,” why he resisted advice to change it, and other onomastic adventures.Jack taught at Queens College (N.Y., not, he pointed out, the one in South Carolina), 1939–57; Washington University (St. Louis, not Seattle or George Washington U.), 1957–64 and again 1978–86; and Yale University (one did not have to add, “New Haven”) 1965–85, where he was Director of the Center for Parliamentary History. At Washington University he was founding Director of the Center for the History of Freedom, which was devoted to a collaborative, multi-volume study of the history of liberty in the West that would realize the dream that Lord Acton called his “madonna of the future”—the difference being that Jack’s vision is already on the way to fulfillment, with the publication of the volume edited by him on Parliament and Liberty from the Reign of Elizabeth to the English Civil War (1992), followed by seven more volumes up to 1996, with more to come.Hexter published books and articles in a variety of fields, finding notoriety especially in his essay of 1958, “Storm over the Gentry,” and later in public jousts with Christopher Hill and others and more retrospective censures of (among others) A. W. Pollard and R. H. Tawney; and he was a master of the Macaulayan art of the review-essay (collected in On Historians, 1979). His article on “Braudel and le monde braudelien” was a mischievous masterpiece of satire which, according to a private communication to Jack, Braudel himself enjoyed in his Olympian way, including the good-natured charge of excessive appetite for facts—“Je vais me dire: ne joue pas trop au Rabelais, sois sage, ne mange pas tout, n’aie les yeux plus gros que le ventre!” (personal letter, 8 February 1973). Several generations of graduate students learned what was involved in doing history from his “The Historian and his Day” (1954), which (like “Storm”), he enjoyed recalling, was rejected by the AHR. He was amused, too, at learning that his article on “The Rhetoric of History” (written for the International Encyclopedia of the Social Sciences) was a harbinger of the rhetorical turn taken a few years later signalled by the historiographical work of Hayden White and others. He was a pioneer, too, in the intensive study of political languages (Visions of Politics on the Eve of the Reformation, 1973), though he lamented the fact that his work on Machiavelli’s and Seyssel’s political vocabulary had to be carried out before the age of computer technology.My first contact with Jack came through my mentor Garrett Mattingly, who was the contemporary historian Jack “most admired” (as he made plain in his contribution to Mattingly’s festschrift). In 1962 Mattingly told me that the plan to publish Hexter’s translation of Seyssel’s Monarchy of France for the Columbia Records Series had to be abandoned because of the first (I think) of Jack’s several heart attacks. I was able to use the mimeographed version for some years before Jack asked me to take over this project, originally visited on him by C. H. McIlwain. It was his suggestion that [End Page 349] we dedicate the collaborative volume, with nice ambiguity, to both McIlwain and Mattingly (who had also been a student of McIlwain) from “two of their deeply devoted students.”In this brief and perhaps overpersonal note (though nothing could be “too personal” for Jack) I will not add further to the store of Hexterian anecdotes, which I began collecting at Queens College, where Jack had already left the makings of a legend in the 1950s. I would just add... (shrink)

The existence of consciousness in animals may have been overlooked. Continuity in consciousness between humans and animals is predicted by evolutionary theory. However, there are specific methodological difficulties associated with investigating such a phenomenon: it cannot be directly measured; animals, unlike humans, cannot directly tell us about their conscious experience; experiments which have made comparisons to human consciousness cannot detect consciousness of a different form; application of the law of parsimony in science has traditionally led to the conclusion that it (...) does not exist. (shrink)

The paper uses questionnaire responses provided by a sample of ethical investors to investigate willingness to sacrifice ethical considerations for financial reward. The paper examines the amount of financial reward necessary to cause an ethical investor to accept a switch from good ethical performance to poor ethical performance. Conjoint analysis is used to allow quantification of the utilities derived from different combinations of ethical and financial performance. Ethical investors are shown to vary in their willingness to sacrifice ethical for financial (...) performance, and hence to display more heterogeneity than the all-encompassing ‘ethical’ label implies. Because of the existence of sub-groups of ethical investors with different attitudes towards financial reward, an attempt has been made to associate observable investors’ characteristics with their level of willingness to trade-off morality for cash. One sub-group of investors in particular appears highly resistant to the idea of accepting higher financial return as compensation for poor ethical performance. This unwillingness casts doubt on Jensen and Meckling’s widely reported claim that trade-off behaviour is ubiquitous in all areas of life. (shrink)

The time taken to react voluntarily to a stimulus is far longer than can be accounted for by ordinary processes of nerve conduction and synaptic delay, and varies unpredictably from trial to trial. Though random, the distribution of reaction times usually follows a relatively simple law, which in turn can be explained by the LATER model, in which a decision signal, representing belief in the existence of the target, rises in response to incoming sensory evidence from an initial value to (...) a criterion level at which action is initiated. But the rate of rise fluctuates randomly from trial, to an extent that cannot be explained by sensory noise at the input. These conclusions, confirmed by recording from neurons in the frontal eye fields, suggest that the randomness of reaction time is due to a deliberate, gratuitous, neural process which confers certain biological advantages as well as having implications for general ideas about the nature of ‘free will'. (shrink)

The experience of newborn screening for Krabbe disease in New York State demonstrates the ethical problems that arise when screening programs are expanded in the absence of true understanding of the diseases involved. In its 5 years of testing and millions of dollars in costs, there have been very few benefits, and the testing has uncovered potential cases of late-onset disease that raise difficult ethical questions in their own right. For these reasons, we argue that Krabbe screening should only be (...) continued as a research project that includes the informed consent of parents to the testing. (shrink)